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The Evolution of AI in Supply Chain

Over my career in supply chain leadership, I’ve seen AI evolve from Predictive AI, which analyzes past data, to Generative AI, which creates alternative scenarios. Now, we are entering the era of Agentic AI—and this is the biggest shift yet.

What Is Agentic AI and Why Does It Matter?

AI Thought Leader Bernard Marr defines Agentic AI as systems that act autonomously, taking proactive steps instead of waiting for human input. Unlike traditional AI, these systems initiate actions, adapt in real time, and continuously learn.

Agentic AI has three defining features:

  • Autonomy – Operating without constant human guidance.
  • Adaptability – Learning from outcomes and refining strategies.
  • Goal Orientation – Acting with clear objectives to drive business results.

With increasing supply chain complexity and disruptions, AI must do more than analyze and predict—it must act.

AI’s Evolution Mirrors Autonomous Driving

The journey to Agentic AI reminds me of how autonomous driving has progressed. Cars didn’t progress from manual to self-driving overnight. Instead, they evolved in stages:

  1. Assisted AI (Such as Early Driver Assistance) – AI provides insights, but humans make final decisions.
  1. Semi-Autonomous AI (Comparable to Adaptive Cruise Control & Lane Assist) – AI takes action with human oversight
  1. Fully Autonomous AI (Like Self-Driving Vehicles at Level 4/5) – AI makes real-time decisions independently

We are already seeing assisted AI and semi-autonomous AI in supply chain planning, with automated reordering, shipment rerouting, and real-time adjustments. As trust in AI grows, these systems will handle increasingly complex tasks with full autonomy.

How will Supply Chain Challenges be Solved with Agentic AI?

1. Reducing Decision Latency

Traditional AI generates insights, but human intervention slows execution. This delay—decision latency—is costly in disruption scenarios.

Agentic AI removes this lag by taking real-time action. If a supplier shuts down, AI can automatically reroute procurement, preventing delays. Companies like NCR and Carrier already use AI-powered planning to speed up decision-making.

2. Proactive Risk Mitigation

Generative AI can model scenarios, but decision-makers still have to act. Agentic AI goes further by testing, selecting, and executing the best option automatically.

For example, if a port strike disrupts shipping, AI can reroute freight, shift inventory, and prevent bottlenecks—without waiting for human approval. Businesses using Salesforce-integrated AI solutions are already seeing faster, smarter responses to disruptions.

3. Adapting to Demand Volatility

I’ve worked in industries where demand volatility makes traditional forecasting unreliable. Agentic AI solves this by predicting shifts and dynamically adjusting inventory, pricing, and supplier orders.

Companies using ketteQ’s AI-driven supply chain planning, capably report greater forecast accuracy and resilience, which are critical for staying competitive.

4. Creating Self-Healing Supply Chains

Resilient supply chains detect issues early and respond instantaneously.

Agentic AI builds self-healing networks by identifying inefficiencies, learning from failures, and fixing problems before they escalate. If a manufacturing delay occurs, AI can reschedule workloads, shift resources, and notify teams—without manual intervention.

5. Enhancing Human Roles, Not Replacing Them

Some worry that AI will replace supply chain professionals, but the reality is that Agentic AI enhances their work by eliminating repetitive tasks. Instead of managing disruptions manually, planners can focus on strategy and innovation while AI handles real-time execution.

According to a Gartner survey, 67% of supply chain leaders say their digital transformation efforts are slowed by a lack of skilled labor.¹ As a result, many planning decisions go unmade or are delayed—leading to inefficiencies, lost revenue, and higher costs. Agentic AI changes that equation by automating the thousands of small, everyday decisions that often slip through the cracks, allowing human planners to focus on the exceptions, the edge cases, and the strategic calls that create the most value.

Yann LeCun, Chief AI Scientist at Meta, emphasizes that AI must understand real-world complexities to reach full autonomy. He asks:

“How can machines learn to reason and plan as efficiently as humans?”

For supply chains, this means AI must do more than process data—it must make informed decisions and act accordingly.

The Future: AI-Driven Supply Chains Are Coming

Just as autonomous driving didn’t happen overnight, Agentic AI will evolve in stages. Companies slow to adopt AI risk falling behind, while early adopters will gain unmatched agility and efficiency.

Businesses already using AI-powered adaptive planning are optimizing supply chains faster, smarter, and with greater precision. The real question is: How quickly will companies embrace this shift?

Coming Soon: The AI Innovation Guide

To help supply chain leaders prepare for this transformation, Chris Amet, CTO of ketteQ, and I are co-authoring an AI Innovation Guide. This guide will explore how Predictive, Generative, and Agentic AI are shaping the future of supply chain planning.

We’ll provide practical adoption strategies, real-world case studies, and a framework for AI-driven supply chains. Stay tuned!

Let’s Talk

How is AI evolving in your supply chain? What challenges do you think Agentic AI can solve?

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About the author

Cheryl Capps
Cheryl Capps
ketteQ EAB Member

Cheryl Capps is a seasoned global operations and supply chain executive with a strong track record of leading transformation and driving results across complex organizations. She has held senior leadership roles at Corning Incorporated, Bristol-Myers Squibb, and General Motors, where she led global teams in procurement, manufacturing, quality, and supply chain. Known for her strategic mindset and operational excellence, Cheryl builds high-performing teams that deliver innovation, agility, and lasting impact. She currently serves as an Executive Advisory Board Member at ketteQ, supporting the advancement of adaptive supply chain planning solutions.